The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 2021

Filed:

Aug. 03, 2017
Applicants:

Incheon University Industry Academic Cooperation Foundation, Incheon, KR;

Ajou University Industsry-academic Cooperation Foundation, Suwon-si, KR;

Inventors:

Kyung Min Park, Anyang-si, KR;

Ki Dong Park, Seoul, KR;

Su Jin Park, Incheon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/08 (2006.01); A61L 27/52 (2006.01); A61K 47/42 (2017.01); A61L 24/10 (2006.01); A61L 24/00 (2006.01); A61L 27/22 (2006.01); C08L 89/06 (2006.01); C08J 3/24 (2006.01); C08J 3/075 (2006.01);
U.S. Cl.
CPC ...
A61L 24/104 (2013.01); A61K 47/42 (2013.01); A61L 24/0031 (2013.01); A61L 27/222 (2013.01); A61L 27/52 (2013.01); C08J 3/075 (2013.01); C08J 3/24 (2013.01); C08L 89/06 (2013.01); A61L 2300/802 (2013.01); A61L 2400/06 (2013.01); C08L 2201/52 (2013.01); C08L 2203/02 (2013.01); C08L 2312/00 (2013.01);
Abstract

A preparation method of calcium peroxide-mediated in situ crosslinkable hydrogel as a sustained oxygen-generating matrix, includes: a) reacting a natural or a synthetic polymer with Traut's reagent (TR) in a solvent, and synthesizing a polymer derivative having thiol group in backbone of the polymer derivative; and b) mixing and reacting a solution of the polymer derivative having thiol group with calcium peroxide (CaO), and thereby forming a hydrogel, wherein in the step b), disulfide bonds (—S—S) are induced between backbones of the polymer derivative having thiol group attached by decomposition of calcium peroxide (CaO), and thereby in situ crosslinking is formed.


Find Patent Forward Citations

Loading…