The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 2021

Filed:

Oct. 10, 2019
Applicant:

Krystal Biotech, Inc., Pittsburgh, PA (US);

Inventors:

Suma Krishnan, San Francisco, CA (US);

Pooja Agarwal, Mars, PA (US);

Assignee:

Krystal Biotech, Inc., Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/763 (2015.01); A61K 9/00 (2006.01); A61K 38/17 (2006.01); A61K 38/39 (2006.01); A61K 48/00 (2006.01); C12N 9/02 (2006.01); C07K 14/78 (2006.01); A61K 9/06 (2006.01); A61K 47/38 (2006.01);
U.S. Cl.
CPC ...
A61K 35/763 (2013.01); A61K 9/0014 (2013.01); A61K 38/1748 (2013.01); A61K 38/39 (2013.01); A61K 48/005 (2013.01); C07K 14/78 (2013.01); C12N 9/0071 (2013.01); C12Y 114/11004 (2013.01); A61K 9/06 (2013.01); A61K 47/38 (2013.01); C12N 2710/16643 (2013.01);
Abstract

The present disclosure relates, in part, to pharmaceutical compositions comprising one or more polynucleotides suitable for enhancing, increasing, augmenting, and/or supplementing the levels of Collagen alpha-1 (VII) chain polypeptide and/or Lysyl hydroxylase 3 polypeptide and/or Keratin type I cytoskeletal 17 polypeptide in a subject. The present disclosure also relates, in part, to pharmaceutical compositions and methods of use for providing prophylactic, palliative, or therapeutic relief of a wound, disorder, or disease of the skin in a subject, including a subject having, or at risk of developing, one or more symptoms of epidermolysis bullosa.


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