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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11185553 B1

PDFFull Text
Date of Patent:
Nov. 30, 2021

Filed:

Oct. 31, 2017

Pharmaceutical composition for preventing or treating ischemic-reperfusion injury comprising bile acids

Applicant:

Samsung Life Public Welfare Foundation, Seoul, KR;

Inventors:

Hyeon Cheol Gwon, Seoul, KR;

Hyung Suk Jang, Seoul, KR;

Assignee:

SAMSUNG LIFE PUBLIC WELFARE FOUNDATION, Seoul, KR;

Attorneys:

Ping Wang

Morris, Manning & Martin LLP

Primary Examiner:

Yevgeny Valenrod

Int. Cl.
CPC ...
A61K 31/575 (2006.01); A61P 9/10 (2006.01); A23L 33/10 (2016.01); A23L 29/00 (2016.01);
U.S. Cl.
CPC ...
A61K 31/575 (2013.01); A23L 29/035 (2016.08); A23L 33/10 (2016.08); A61P 9/10 (2018.01); A23V 2200/326 (2013.01); A23V 2250/03 (2013.01);
Abstract

The present invention relates to a composition for preventing, treating, or alleviating ischemia-reperfusion injury, containing bile acid. According to the present invention, bile acid increases intranuclear beta-catenin levels, interferes with the opening of a mitochondria permeable transition pore (mPTP), and has excellent effects, in ischemia-reperfusion injury animal models, of alleviating tissue injury and reducing the size of infarcts, thereby being usable in the prevention, treatment, or alleviation of ischemia-reperfusion injury.

Find Patent Forward Citations

Gwon, Hyeon. (2021). Pharmaceutical composition for preventing or treating ischemic-reperfusion injury comprising bile acids (U.S. Patent No. 11185553). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11185553

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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