The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 30, 2021
Filed:
Feb. 26, 2020
Applicant:
Epizyme, Inc., Cambridge, MA (US);
Inventors:
Richard Chesworth, Concord, MA (US);
Lorna Helen Mitchell, Cambridge, MA (US);
Gideon Shapiro, Gainesville, FL (US);
Assignee:
Epizyme, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); C07D 231/12 (2006.01); C07D 401/04 (2006.01); C07D 413/08 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); C07D 401/02 (2006.01); C07D 231/10 (2006.01); C07D 413/02 (2006.01); C07D 405/04 (2006.01); C12N 9/10 (2006.01); A61K 31/4155 (2006.01);
U.S. Cl.
CPC ...
A61K 31/415 (2013.01); A61K 31/4155 (2013.01); A61K 31/454 (2013.01); A61K 31/5377 (2013.01); C07D 231/10 (2013.01); C07D 231/12 (2013.01); C07D 401/02 (2013.01); C07D 401/04 (2013.01); C07D 405/04 (2013.01); C07D 413/02 (2013.01); C07D 413/08 (2013.01); C12N 9/1007 (2013.01); C12Y 201/01125 (2013.01);
Abstract
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.