The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 30, 2021
Filed:
Apr. 09, 2020
Liminal Biosciences Inc., Comberton, GB;
Lyne Gagnon, Laval, CA;
Brigitte Grouix, Montreal, CA;
LIMINAL BIOSCIENCES LIMITED, Cambridge, GB;
Abstract
The present invention concerns the use of compounds for preventing and/or treating osteoporosis, for stimulating bone formation, for stimulating bone remodeling, for stimulating the differentiation and mineralization of osteoblasts, for inhibiting bone resorption and for modulating serum level of adiponectin in a subject. These uses have been found for compounds represented by Formula I and pharmaceutically acceptable salts thereof, wherein A is Calkyl, Calkyl, Calkenyl, Calkenyl, C(O)—(CH)—CHor CH(OH)—(CH)—CHwherein n is 3 or 4; Ris H, F or OH; Ris H, F, OH, Calkyl, Calkenyl, Calkenyl, C(O)(CH)—CHor CH(OH)—(CH)—CHwherein n is 3 or 4; Ris H, F, OH or CHPh; Ris H, F, or OH; Q is 1) (CH)C(O)OH wherein m is 1 or 2, 2) CH(F)—C(O)OH, 3) CF—C(O)OH, or 4) C(O)—C(O)OH.