The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 30, 2021

Filed:

Jul. 28, 2017
Applicant:

Toray Industries, Inc., Tokyo, JP;

Inventors:

Suguru Takaki, Kamakura, JP;

Satoshi Minakami, Kamakura, JP;

Kotoe Ohta, Kamakura, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 31/485 (2006.01); A61K 9/48 (2006.01); A61K 9/14 (2006.01); A61K 47/10 (2017.01); A61K 9/16 (2006.01); A61K 47/02 (2006.01); A61K 47/08 (2006.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01); A61P 17/04 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2013 (2013.01); A61K 9/14 (2013.01); A61K 9/16 (2013.01); A61K 9/20 (2013.01); A61K 9/2009 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/48 (2013.01); A61K 31/485 (2013.01); A61K 47/02 (2013.01); A61K 47/08 (2013.01); A61K 47/10 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); A61P 17/04 (2018.01);
Abstract

A solid preparation includes a 4,5-epoxymorphinan derivative or a pharmaceutically acceptable acid addition salt thereof, which is stable to light even without light shielding coating. The solid preparation includes an active ingredient composed of a 4,5-epoxymorphinan derivative or a pharmaceutically acceptable acid addition salt thereof, and one or more stabilizing agents selected from the group consisting of n-propyl gallate, sodium hydrogensulfite, dibutylhydroxytoluene, butylhydroxyanisole, tocopherol and D-isoascorbic acid, wherein the amount of the above active ingredient is 0.00001 to 0.01% by weight of the solid preparation, and the amount of the above stabilizing agent is 0.005 to 5% by weight of the solid preparation.


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