The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2021
Filed:
Nov. 07, 2013
Applicant:
Five3 Genomics, Llc, Santa Cruz, CA (US);
Inventor:
John Zachary Sanborn, Santa Cruz, CA (US);
Assignee:
Five3 Genomics, LLC, Culver City, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G16B 20/20 (2019.01); G16B 20/00 (2019.01); G16B 30/00 (2019.01); G16B 30/10 (2019.01); G16B 40/00 (2019.01); G16B 20/10 (2019.01);
U.S. Cl.
CPC ...
G16B 20/20 (2019.02); G16B 20/00 (2019.02); G16B 30/00 (2019.02); G16B 30/10 (2019.02); C12Q 2600/156 (2013.01); G16B 20/10 (2019.02); G16B 40/00 (2019.02);
Abstract
Systems and methods of genomic analysis are presented that provide a framework to determine a tumor's clonality, the number and proportion of all major clones, and the variants that distinguish them. Contemplated systems and methods also allow phasing mutations to parental alleles to so time their emergence within the population of tumor cells, and provide an accurate estimate of the amount of contaminating normal tissue that was present in the tumor biopsy.