The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 23, 2021

Filed:

Jan. 25, 2019
Applicant:

Leica Microsystems Cms Gmbh, Wetzlar, DE;

Inventors:

Florian Ziesche, Mannheim, DE;

Kai Walter, Schriesheim, DE;

Juergen Reymann, Heidelberg, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06T 7/00 (2017.01); G06T 5/00 (2006.01); G06T 7/13 (2017.01); A61B 1/04 (2006.01); A61B 90/20 (2016.01);
U.S. Cl.
CPC ...
G06T 5/003 (2013.01); A61B 1/043 (2013.01); A61B 90/20 (2016.02); G06T 5/002 (2013.01); G06T 7/13 (2017.01); G06T 2207/10056 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/10068 (2013.01); G06T 2207/20012 (2013.01);
Abstract

A method for a deconvolution of a digital input image (I(x)) having a plurality of input voxels (x), in particular a digital input image obtained from a medical observation device, such as a microscope or endoscope and/or using fluorescence, includes computing a local signal-to-noise ratio (SNR(x)) within an input region (R(x)) of the digital input image, the input region consisting of a subset of the plurality of input voxels of the digital input image and surrounding the current input voxel. A noise component (β(SNR)) is computed from the local signal-to-noise ratio, the noise component representing image noise (([h*f](x), n(x)) in the deconvolution. The noise component is limited to a predetermined minimum noise value (β) for a local signal-to-noise ratio above a predetermined upper SNR threshold value (SNR) and is limited to a predetermined maximum noise value (β) for a local signal-to-noise ratio below a predetermined lower SNR threshold value (SNR).


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