The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2021
Filed:
Oct. 25, 2018
Applicant:
Universität Heidelberg, Heidelberg, DE;
Inventors:
Dagmar Hildebrand, Dossenheim, DE;
Klaus Heeg, Heidelberg, DE;
Florian Uhle, Heidelberg, DE;
Markus Weigand, Wettenberg, DE;
Assignee:
UNIVERSITÄT HEIDELBERG, Heidelberg, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6876 (2018.01); C07K 14/435 (2006.01); G01N 33/68 (2006.01); C12Q 1/6888 (2018.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); C07K 14/435 (2013.01); C12Q 1/6876 (2013.01); C12Q 1/6888 (2013.01); C12Q 2600/118 (2013.01); G01N 2800/26 (2013.01);
Abstract
The invention refers to a method for in vitro diagnosis of a severe infection comprising determining delta-like ligand 1 protein or a nucleotide sequence coding for delta-like ligand 1 protein in a biological sample wherein an elevated level of expression of delta-like ligand 1 protein or a nucleotide sequence coding for delta-like ligand 1 protein is indicative of a severe infection; and the use of delta-like ligand 1 protein as a biomarker for in vitro diagnosis of a severe infection such as sepsis.