The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 23, 2021

Filed:

Apr. 24, 2018
Applicants:

Biomerieux, Marcy l'Etoile, FR;

Hospices Civils DE Lyon (Hcl), Lyons, FR;

Inventors:

Fanny Davin, Saint Jean de Muzols, FR;

Alain Lepape, Saint-Genis Laval, FR;

Guillaume Monneret, Lyons, FR;

Florence Frager, Lyons, FR;

Assignees:

BIOMERIEUX, Marcy l'Etoile, FR;

HOSPICES CIVILS DE LYON (HCL), Lyons, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/04 (2006.01); C12Q 1/6876 (2018.01); C12Q 1/6883 (2018.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); C12Q 1/6883 (2013.01); G01N 33/68 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); C40B 30/04 (2013.01);
Abstract

The present invention relates to a process for determining in vitro the immune status of an individual according to which: (a) a blood sample from the individual is provided, (b) at least two reagents specific to at least two products of expression of at least two target genes are provided; (c) the expression of said at least two target genes is determined, and (d) the expression of said at least two target genes respectively is compared with a reference expression, with a change in the expression of said at least two target genes relative to their reference expression indicating that the individual's immune status has changed, and a correlation between the expression of said at least two target genes with their reference expression indicating that the individual's immune status is normal; as well as a kit for determining said immune status of the individual.


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