The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2021
Filed:
Nov. 16, 2018
Applicant:
Medical Diagnostic Laboratories, Llc, Hamilton, NJ (US);
Inventor:
Tatyana Naryshkina, East Brunswick, NJ (US);
Assignee:
Medical Diagnostic Laboratories, LLC, Hamilton, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/79 (2006.01); C12N 9/02 (2006.01); G01N 33/50 (2006.01); C12Q 1/48 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12N 15/79 (2013.01); C12N 9/0069 (2013.01); C12N 9/12 (2013.01); C12Q 1/485 (2013.01); G01N 33/5005 (2013.01); C07K 2319/60 (2013.01); C12Y 113/12009 (2013.01);
Abstract
Disclosed are methods of determining activity of CDK4 and CDK6 variants upon exposure to CDK inhibitors, methods for determining activity of a Rb variant, methods for determining the activity of a p16 variant in a cell, and methods for determining the sensitivity of a CDK4 variant or a CDK6 variant to p16 in a cell. Stable cell lines for determining activity of CDK4 variants, CDK6 variants, Rb variants, and p16 variants are also disclosed.
Quick Actions:
Naryshkina, Tatyana. (2021). Cell-based assay for determining activity in the retinoblastoma pathway (U.S. Patent No. 11180766). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11180766
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile