The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2021
Filed:
Jul. 23, 2019
Applicant:
Affimed Gmbh, Heidelberg, DE;
Inventors:
Thorsten Ross, Edingen-Neckarhausen, DE;
Ivica Fucek, Hattersheim, DE;
Kristina Ellwanger, Heidelberg, DE;
Michael Weichel, Bischofsheim, DE;
Uwe Reusch, Maikammer, DE;
Stefan Knackmuss, Planckstadt, DE;
Erich Rajkovic, Schriessheim, DE;
Martin Treder, Heidelberg, DE;
Assignee:
Affimed GMBH, Heidelberg, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/283 (2013.01); A61P 35/00 (2018.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01);
Abstract
The invention relates to a multispecific antigen-binding molecule specifically binding to CD16A and consisting of two polypeptide chains, wherein each polypeptide chain comprises at least four variable domains from the N-terminus to the C-terminus in the order: VH_BCMA-VL_CD16A-VH_CD16A-VL_BCM.