The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 23, 2021

Filed:

Jan. 29, 2019
Applicants:

Metro International Biotech, Llc, Birmingham, MI (US);

Newsouth Innovations Pty Ltd, Sydney, AU;

Inventors:

Jonathan N. Kremsky, Arlington, MA (US);

Bruce Szczepankiewicz, Hopkinton, MA (US);

Hamish Toop, Sydney, AU;

Jonathan Morris, Sydney, AU;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/048 (2006.01);
U.S. Cl.
CPC ...
C07H 19/048 (2013.01);
Abstract

Provided herein are compounds of Formula (I) and their salts, and compositions comprising such compounds that are useful for increasing the amount of NADin cells. Also disclosed are methods of using the disclosed compounds and compositions for treating, for example, diseases or disorders related to aging or stress, diabetes, obesity, mitochondrial diseases, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing.


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