The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2021
Filed:
Sep. 10, 2020
Applicant:
Omniome, Inc., San Diego, CA (US);
Inventors:
Denis Malyshev, San Diego, CA (US);
Aaron W. Feldman, San Diego, CA (US);
Assignee:
OMNIOME, INC., San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/00 (2006.01); C07H 19/10 (2006.01);
U.S. Cl.
CPC ...
C07H 1/00 (2013.01); C07H 19/10 (2013.01);
Abstract
Disclosed herein, inter alia, are methods for modifying a nucleotide, for example including reacting a nucleotide having a 3'-O-oxime moiety such as with a reagent having an —ONHmoiety to produce a nucleotide having a 3′-O—NHmoiety such as wherein the reagent having the —ONHmoiety further comprises alkyl, alkenyl, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl, heteroaryl, heteroalicyclyl, aralkyl, heteroaralkyl, or (heteroalicyclyl)alkyl.