The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2021
Filed:
Jul. 26, 2018
Applicant:
Eli Lilly and Company, Indianapolis, IN (US);
Inventors:
Michael James Genin, Danville, IN (US);
William Glen Holloway, Brownsburg, IN (US);
Richard Duane Johnston, Greenfield, IN (US);
John Richard Morphy, Surrey, GB;
Qing Shi, Carmel, IN (US);
Assignee:
ELI LILLY AND COMPANY, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); A61K 31/4985 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01);
Abstract
The present invention provides a compound of Formula (I), wherein X is H or C1-C3 alkyl optionally substituted with hydroxyl; Y is H, hydroxy, or methyl; R is ethyl, n-propyl, cyclopropyl, or Formula (II); and A is methyl, cyclopropyl or trifluoromethyl; or a pharmaceutically acceptable salt thereof; with the proviso that when X and Y are both H and R is n-propyl, then A is other than methyl; for use as a human PDE1 inhibitor.