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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11180474 B1

PDFFull Text
Date of Patent:
Nov. 23, 2021

Filed:

Jul. 27, 2017

Dimethoxyphenyl substituted indole compounds as tlr7, tlr8 or tlr9 inhibitors

Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Alaric J. Dyckman, Lawrenceville, NJ (US);

Dharmpal S. Dodd, Monmouth Junction, NJ (US);

Christopher P. Mussari, Princeton, NJ (US);

Tasir S. Haque, Yardley, PA (US);

Michael A. Poss, Lawrenceville, NJ (US);

Louis J. Lombardo, Belle Mead, NJ (US);

John E. Macor, Washington Crossing, PA (US);

Laxman Pasunoori, Warangal, IN;

Sreekantha Ratna Kumar, Bangalore, IN;

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:

Gary Greenblatt

Primary Examiner:

Heidi Reese

Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01); C07D 451/02 (2006.01); C07D 401/04 (2006.01); C07D 413/14 (2006.01); A61P 37/06 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61P 37/06 (2018.01); C07D 401/04 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 451/02 (2013.01);
Abstract

Disclosed are compounds of Formula (I) or a salt thereof, wherein R, R, R, R, m, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

Find Patent Forward Citations

Dyckman, Alaric. (2021). Dimethoxyphenyl substituted indole compounds as tlr7, tlr8 or tlr9 inhibitors (U.S. Patent No. 11180474). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11180474

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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