The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2021
Filed:
Jul. 25, 2016
Applicant:
Midatech Limited, Cardiff, GB;
Inventors:
Africa Garcia Barrientos, Sopelana, ES;
Esther de Torres Dominguez, Elgoibar, ES;
Assignee:
MIDATECH Limited, Cardiff, GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 47/64 (2017.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6929 (2017.08); A61K 9/51 (2013.01); A61K 47/64 (2017.08);
Abstract
The invention provides a nanoparticle comprising: a core comprising a metal and/or a semiconductor; and a plurality of ligands covalently linked to the core, wherein said ligands comprise: at least one liver-targeting ligand; at least one payload ligand comprising a bioactive agent; and at least one dilution ligand comprising a carbohydrate. Also provided are pharmaceutical compositions comprising the nanoparticles, medical uses thereof, including in the treatment and imaging of liver cancers, and processes for the production of the nanoparticles.