The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2021
Filed:
Mar. 06, 2017
Compositions and method for administering ppargamma agonists, surfactant peptides and phosopholipids
Lundquist Institute for Biomedical Innovation AT Harbor—ucla Medical Center, Torrance, CA (US);
Virender K. Rehan, Torrance, CA (US);
John S. Torday, Torrance, CA (US);
Frans J. Walther, Torrance, CA (US);
Alan J. Waring, Torrance, CA (US);
Larry M. Gordon, Torrance, CA (US);
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR—UCLA MEDICAL CENTER, Torrance, CA (US);
Abstract
The present disclosure provides compositions and therapies that can address both the symptoms and disorders associated with insufficient surfactant production and hyperoxia. In one embodiment, the composition can be formulated for aerosol delivery during ventilation therapy. The composition can comprise one or more of the following: a PPAR gamma agonist, a surfactant peptide, and one or more phospholipids. The compositions are formulated to provide the complementary benefits of reducing the likelihood of developing or the severity of RDS in infants, as well as protecting and promoting lung maturation in a hyperoxic environment.