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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11179383 B1

PDFFull Text
Date of Patent:
Nov. 23, 2021

Filed:

Oct. 29, 2019

Compounds for inhibition of α4β7 integrin

Applicant:

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Peter A. Blomgren, Issaquah, WA (US);

Taryn Campbell, Seattle, WA (US);

Jayaraman Chandrasekhar, Redmond, WA (US);

Christopher T. Clark, Seattle, WA (US);

Julian A. Codelli, Seattle, WA (US);

Kevin S. Currie, North Bend, WA (US);

Jeffrey E. Kropf, Issaquah, WA (US);

Yasamin Moazami, Seattle, WA (US);

Nicole Nava, Seattle, WA (US);

Leena Patel, Seattle, WA (US);

Stephane Perreault, Brier, WA (US);

Jason K. Perry, San Francisco, CA (US);

Kassandra F. Sedillo, Princeton, NJ (US);

Natalie Seeger, Seattle, WA (US);

Kirk L. Stevens, Bothell, WA (US);

Jennifer Anne Treiberg, Redmond, WA (US);

Suet C. Yeung, Redmond, WA (US);

Zhongdong Zhao, Bellevue, WA (US);

Assignee:

GILEAD SCIENCES, INC., Foster City, CA (US);

Attorney:
Primary Examiner:

Charanjit Aulakh

Int. Cl.
CPC ...
C07D 215/02 (2006.01); A61K 31/47 (2006.01); A61K 31/352 (2006.01); A61K 31/4709 (2006.01); A61K 31/497 (2006.01); A61K 31/501 (2006.01); A61K 31/513 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); C07D 215/14 (2006.01); C07D 311/58 (2006.01); C07D 401/10 (2006.01); C07D 403/10 (2006.01); C07D 405/10 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/10 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/47 (2013.01); A61K 31/352 (2013.01); A61K 31/4709 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/513 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); C07D 215/14 (2013.01); C07D 311/58 (2013.01); C07D 401/10 (2013.01); C07D 403/10 (2013.01); C07D 405/10 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/10 (2013.01); C07D 471/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.

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