The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 23, 2021
Filed:
Jul. 09, 2019
Novocure Gmbh, Root, CH;
Karnit Gotlib, Tirat Carmet, IL;
Einav Zeevi, Zichron Yaakov, IL;
Rosa S. Schnaiderman, Haifa, IL;
Tali Voloshin-Sela, Kibbutz Gvat, IL;
Moshe Giladi, Moshav Herut, IL;
Adrian Kinzel, Bochum, DE;
Eilon Kirson, Ramat Hasharon, IL;
Uri Weinberg, Binyamina, IL;
Yoram Palti, Haifa, IL;
Shiri Davidi, D.N. Galil Maharavi, IL;
Novocure GmbH, Root, CH;
Abstract
Viability of cancer cells (e.g., hepatocellular carcinoma cells) can be reduced by administering sorafenib to the cancer cells and applying an alternating electric field with a frequency between 100 and 400 kHz to the cancer cells. Viability of cancer cells (e.g., hepatocellular carcinoma cells) disposed in a body of a living subject can be reduced by administering sorafenib to the subject and applying an alternating electric field with a frequency between 100 and 400 kHz to the cancer cells. Notably, experiments show that the combination of sorafenib and the alternating electric field produces synergistic results both in vitro and in vivo.