The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2021

Filed:

Feb. 27, 2013
Applicant:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Cassandra B. Jabara, Ridgefield, CT (US);

Jeffrey A. Anderson, Pennington, NJ (US);

Ronald I. Swanstrom, Chapel Hill, NC (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6853 (2018.01); C12Q 1/689 (2018.01); C12Q 1/70 (2006.01); G16B 30/10 (2019.01); G16B 30/00 (2019.01); C12Q 1/6874 (2018.01);
U.S. Cl.
CPC ...
G16B 30/10 (2019.02); C12Q 1/689 (2013.01); C12Q 1/6853 (2013.01); C12Q 1/6874 (2013.01); C12Q 1/703 (2013.01); G16B 30/00 (2019.02); C12Q 2600/156 (2013.01); C12Q 2600/16 (2013.01); C12Q 2600/172 (2013.01);
Abstract

Methods and uses for molecular tags are disclosed. Molecular tags may be attached to nucleic acid molecules. The attachment of the nucleic acid molecules prior to PCR amplification and sequencing improves the accuracy of genetic analysis and detection of genetic variations and diversity. Molecular tags may also be used for detection of drug-resistant variants. Methods for using molecular tags for determining and correcting PCR errors and/or sequencing error are also disclosed.


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