The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2021

Filed:

May. 07, 2019
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventors:

Poorya Sabounchi, Atherton, CA (US);

Behnam Javanmardi, Saratoga, CA (US);

Tarun Khurana, Fremont, CA (US);

Philip Paik, Chula Vista, CA (US);

Yan-You Lin, Fremont, CA (US);

Assignee:

Illumina, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 7/00 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); B01L 3/5027 (2013.01); B01L 3/502707 (2013.01); B01L 3/502738 (2013.01); B01L 7/52 (2013.01); C12Q 1/6806 (2013.01); B01L 3/502715 (2013.01); B01L 2200/10 (2013.01); B01L 2200/12 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0809 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0874 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/123 (2013.01); B01L 2300/165 (2013.01); B01L 2300/1827 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0644 (2013.01); B01L 2400/0655 (2013.01);
Abstract

A stack of fluidics layers of a microfluidic cartridge for sequencing nucleic acid molecules includes a sequencing chamber layer having a sequencing chamber area configured for carrying out clustering and sequencing reactions, and a sequencing chamber bottom layer disposed under the sequencing chamber layer. The sequencing chamber bottom layer has an opening configured to hold an image sensor with the image sensor having an active area disposed under the sequencing chamber area. The sequencing chamber area spans substantially all of the active area of the image sensor. The stack of fluidics layers includes a flexible printed circuit board (PCB) layer under the sequencing chamber bottom layer, and a fluidics channels layer disposed under the flexible PCB layer. The fluidics channels layer includes fluidics channels that are configured to deliver reactants to the sequencing chamber area. The fluidics channels do not substantially overlap with the active area of the image sensor.


Find Patent Forward Citations

Loading…