The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2021

Filed:

Apr. 07, 2016
Applicants:

The Regents of the University of California, Oakland, CA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Jeff Hasty, Encinitas, CA (US);

Lev Tsimring, San Diego, CA (US);

Muhammad Omar Din, San Diego, CA (US);

Arthur Prindle, San Diego, CA (US);

Sangeeta Bhatia, Lexington, MA (US);

Tal Danino, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01); A61K 35/74 (2015.01); A61K 38/16 (2006.01); C12N 1/06 (2006.01); C12N 1/20 (2006.01); C12N 15/63 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/74 (2013.01); A61K 35/74 (2013.01); A61K 38/16 (2013.01); C12N 1/06 (2013.01); C12N 1/20 (2013.01); C12N 15/63 (2013.01); C12P 21/02 (2013.01);
Abstract

Some embodiments described herein relate to cells which have been genetically engineered to release a polypeptide when a population of the cells reaches a desired density. In some embodiments, the released polypeptide may be a therapeutic polypeptide. In some embodiments, the therapeutic polypeptide kills tumor cells or which inhibits the growth of tumor cells.


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