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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11174485 B1

PDFFull Text
Date of Patent:
Nov. 16, 2021

Filed:

Sep. 01, 2015

Protein muns that can form inclusions in the endoplasmic reticulum, methods for the use thereof and uses of same

Applicant:

Universidade DE Santiago DE Compostela, Santiago de Compostela, ES;

Inventors:

José Manuel Martínez Costas, Santiago de Compostela, ES;

Natalia Barreiro Piñeiro, Santiago de Compostela, ES;

Francisco Javier Benavente Martínez, Santiago de Compostela, ES;

Assignee:

UNIVERSID ADE DE SANTIAGO DE COMPOSTELA, Santiago de Compostela, ES;

Attorneys:

Hultquist, PLLC

Steven J. Hultquist

Primary Examiner:

Paul J Holland

Int. Cl.
CPC ...
C12N 15/62 (2006.01); C07K 19/00 (2006.01); C07K 14/14 (2006.01); C12N 5/10 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); G01N 33/50 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/625 (2013.01); C07K 14/005 (2013.01); C07K 14/14 (2013.01); C07K 19/00 (2013.01); C12N 5/10 (2013.01); C12N 7/00 (2013.01); C12N 15/62 (2013.01); G01N 33/5076 (2013.01); A61K 39/00 (2013.01); C07K 2319/04 (2013.01); C12N 2720/12222 (2013.01); C12N 2760/20234 (2013.01);
Abstract

The invention relates to a polynucleotide encoding a polypeptide based on the minimum region of the Orthoreovirus muNS protein that can form inclusions in the endoplasmic reticulum, and to said polypeptide. The invention also relates to a purification method and a method for detecting interaction between two polypeptides based on the capacity of some regions of the Orthoreovirus muNS protein to incorporate themselves into the inclusions, together with a peptide of interest.

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