The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2021

Filed:

Apr. 05, 2018
Applicant:

Silence Therapeutics Gmbh, Berlin, DE;

Inventors:

Sibylle Dames, Berlin, DE;

Ute Schaeper, Berlin, DE;

Judith Hauptmann, Berlin, DE;

Christian Frauendorf, Berlin, DE;

Lucas Bethge, Berlin, DE;

Adrien Weingärtner, Berlin, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61P 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61P 7/00 (2018.01); C12N 2310/313 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/351 (2013.01);
Abstract

The present invention relates to products and compositions and their uses. In particular the invention relates to nucleic acid products that interfere with the TMPRSS6 gene expression or inhibits its expression and therapeutic uses such as for the treatment of hemochromatosis, porphyria and blood disorders such as β-thalassemias, sickle cell disease and transfusional iron overload or myelodysplastic syndrome.


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