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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11174318 B1

PDFFull Text
Date of Patent:
Nov. 16, 2021

Filed:

Jun. 21, 2019

Monoclonal antibody targeting a unique sialoglycosylated cancer-associated epitope of cd43

Applicant:

Università Degli Studi Magna Graecia Catanzaro, Catanzaro, IT;

Inventor:

Pierfrancesco Tassone, Catanzaro, IT;

Assignee:

UNIVERSITÀ DEGLI STUDI MAGNA GRAECIA CATANZARO, Catanzaro, IT;

Attorney:

Fenwick & West LLP

Primary Examiner:

Brad Duffy

Assistant Examiner:

Cheom-Gil Cheong

Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); A61K 35/02 (2015.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01); G01N 33/574 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61K 35/02 (2013.01); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C07K 16/2809 (2013.01); G01N 33/57407 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/732 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01);
Abstract

The present invention relates to a monoclonal mouse antibody produced by the hybridoma cell deposited under ICLC accession number ICLC PD n° 16001. Furthermore, the invention relates to an antibody comprising a heavy chain variable region comprising complementarity determining regions CDRH1, CDRH2 and CDRH3, and a light chain variable region comprising complementarity determining regions CDRL1, CDRL2 and CDRL3, wherein CDRH1, CDRH2, CDRH3, CDRL1, CDRL2, and CDRL3 comprise the amino acid sequences GFTFSSFGMH (SEQ ID NO: 1), YISSGSGNFYYVDTVKG (SEQ ID NO: 43), STYYHGSRGAMDY (SEQ ID NO: 3), SASSSVSSMYWY (SEQ ID NO: 4), DTSKMAS (SEQ ID NO: 5), and QQWSSYPPIT (SEQ ID NO: 6), respectively. In addition, the invention relates to antibodies recognizing the same epitope.

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