The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2021
Filed:
May. 21, 2020
International Business Machines Corporation, Armonk, NY (US);
Agency for Science, Technology and Research, Singapore, SG;
Payel Das, Yorktown Heights, NY (US);
Flaviu Cipcigan, Warrington, GB;
James L. Hedrick, Pleasanton, CA (US);
Yi Yan Yang, Singapore, SG;
Kahini Wadhawan, Ferozepur, IN;
Inkit Padhi, White Plains, NY (US);
Enara C Vijil, Millwood, NY (US);
Pang Kern Jeremy Tan, Singapore, SG;
INTERNATIONAL BUSINESS MACHINES CORPORATION, Armonk, NY (US);
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, Singapore, SG;
Abstract
De novo, artificial intelligence (AI) designed antimicrobial peptides (AMPs), antibacterial products comprising the AMPs and methods for treating bacterial infections using the products are provided. In one or more embodiments, the AMPs were designed using conditional latent attribute space sampling (CLaSS). The AMPs comprise up to twenty natural amino acids in length, including one with twelve and another with thirteen natural amino acids in length. The AMPs demonstrate low-toxicity and show high antimicrobial potency against diverse pathogens including multi-medication-resistant Gram negative