The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2021

Filed:

Jun. 02, 2017
Applicant:

Université Laval, Quebec, CA;

Inventors:

Donald Poirier, L'Ancienne-Lorette, CA;

René Maltais, Quebec, CA;

Martin Perreault, Quebec, CA;

Assignee:

UNIVERSITÉ LAVAL, Quebec, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61P 35/00 (2006.01); C07J 41/00 (2006.01); C07J 43/00 (2006.01); C07J 73/00 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); A61P 35/00 (2018.01); C07J 73/005 (2013.01);
Abstract

Estrane-based and androstane-based aminosteroid derivatives are described herein. More specifically, the following piperazinyl-steroid compounds of Formula I, Formula II, Formula III, and Formula IV are described. The compounds display cytotoxicity on a variety of cancer cell lines. A process for producing the compounds and their use in the manufacture of pharmaceutical formulations and/or combinations is also disclosed.


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