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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11174268 B1

PDFFull Text
Date of Patent:
Nov. 16, 2021

Filed:

Mar. 02, 2020

Benzenesulfonamide compouds and their use as therapeutic agents

Applicant:

Xenon Pharmaceuticals Inc., Burnaby, CA;

Inventors:

Jean-Christophe Andrez, Vancouver, CA;

David Earl Bogucki, Surrey, CA;

Kristen Nicole Burford, Burnaby, CA;

Sultan Chowdhury, Surrey, CA;

Charles Jay Cohen, Vancouver, CA;

Shannon Marie Decker, Burnaby, CA;

Christoph Martin Dehnhardt, Burnaby, CA;

Robert Joseph Devita, Westfield, NJ (US);

James Roy Empfield, Natick, MA (US);

Thilo Focken, Burnaby, CA;

Michael Edward Grimwood, North Vancouver, CA;

Syed Abid Hasan, Vancouver, CA;

Qi Jia, Burnaby, CA;

James Philip Johnson, Jr., Burnaby, CA;

Michael Scott Wilson, Burnaby, CA;

Alla Yurevna Zenova, Vancouver, CA;

Assignee:

Xenon Pharmaceuticals Inc., Burnaby, CA;

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Robert H Havlin

Int. Cl.
CPC ...
C07D 491/107 (2006.01); C07D 493/10 (2006.01); C07D 237/20 (2006.01); C07D 213/76 (2006.01); C07D 239/69 (2006.01); C07D 261/16 (2006.01); C07D 263/50 (2006.01); C07D 275/03 (2006.01); C07D 277/52 (2006.01); C07D 285/08 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 487/10 (2006.01); C07D 417/14 (2006.01); C07D 451/06 (2006.01); A61K 31/395 (2006.01); A61K 31/427 (2006.01);
U.S. Cl.
CPC ...
C07D 491/107 (2013.01); A61K 31/395 (2013.01); A61K 31/427 (2013.01); C07D 213/76 (2013.01); C07D 237/20 (2013.01); C07D 239/69 (2013.01); C07D 261/16 (2013.01); C07D 263/50 (2013.01); C07D 275/03 (2013.01); C07D 277/52 (2013.01); C07D 285/08 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 451/06 (2013.01); C07D 487/10 (2013.01); C07D 493/10 (2013.01);
Abstract

This invention is directed to benzenesulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or conditions associated with voltage-gated sodium channels, such as epilepsy and/or epileptic seizure disorders.

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