The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2021
Filed:
Jun. 13, 2016
The Regents of the University of California, Oakland, CA (US);
David Lee Van Vranken, Irvine, CA (US);
Haoping Liu, Irvine, CA (US);
Ilandari Dewage Udara Anulal Premachandra, Los Angeles, CA (US);
Fuqiang Wang, Irvine, CA (US);
Chengtian Shen, Irvine, CA (US);
Kevin Andre Scott, Vista, CA (US);
Shelley Ren-An Lane, Huntington Beach, CA (US);
Aaron David Mood, Fullerton, CA (US);
Stanley Chungsing Hiew, Irvine, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Small molecules comprised of spiroindolinone analogues are provided. Some spiroindolinones are provided with a particular relative stereochemistry in which the indolone carbonyl and all three hydrogens are on the same face of the central pyrrolidine ring. A stereoselective method of synthesis is provided for making some of the spiroindolinones described above. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, fungal infections. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.