The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2021
Filed:
Jul. 16, 2021
Applicant:
King Abdulaziz University, Jeddah, SA;
Inventors:
Moustafa E. El-Araby, Jeddah, SA;
Abdelsattar M. Omar, Jeddah, SA;
Ahmed Esmat, Jeddah, SA;
Farid Ahmed, Jeddah, SA;
Azizah M. Malebari, Jeddah, SA;
Ashraf B. Abdel-Naim, Jeddah, SA;
Thikryat Neamatallah, Jeddah, SA;
Assignee:
King Abdulaziz University, Jeddah, SA;
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/96 (2006.01); C07D 405/06 (2006.01); C07D 307/52 (2006.01); C07C 237/22 (2006.01);
U.S. Cl.
CPC ...
C07D 233/96 (2013.01); C07C 237/22 (2013.01); C07D 307/52 (2013.01); C07D 405/06 (2013.01); C07C 2601/16 (2017.05);
Abstract
Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.