The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2021

Filed:

Dec. 19, 2018
Applicants:

Alexandra Ros, Phoenix, AZ (US);

Daihyun Kim, Mesa, AZ (US);

Jinghui Luo, Covina, CA (US);

Inventors:

Alexandra Ros, Phoenix, AZ (US);

Daihyun Kim, Mesa, AZ (US);

Jinghui Luo, Covina, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B03C 5/02 (2006.01); B03C 5/00 (2006.01); G01N 1/40 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 3/502753 (2013.01); B01L 3/502761 (2013.01); B03C 5/005 (2013.01); B03C 5/026 (2013.01); B03C 5/028 (2013.01); B01L 3/50273 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0816 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0424 (2013.01); B01L 2400/086 (2013.01); B03C 2201/26 (2013.01); G01N 2001/4038 (2013.01); G01N 2015/0038 (2013.01);
Abstract

Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel.


Find Patent Forward Citations

Ros, Alexandra. (2021). Deterministic ratchet for sub-micrometer bioparticle separation (U.S. Patent No. 11173487). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11173487

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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