The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2021
Filed:
Apr. 06, 2018
Applicants:
Janssen Vaccines & Prevention B.v., Leiden, NL;
Bavarian Nordic A/s, Kvistgaard, DK;
Inventors:
Benoit Christophe Stephan Callendret, The Hague, NL;
Kerstin Luhn-Wegmann, Leiden, NL;
Assignees:
Janssen Vaccines & Prevention B.V., Leiden, NL;
Bavarian Nordic A/S, Kvistgaard, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); C12N 15/86 (2006.01); A61K 39/235 (2006.01); A61P 37/04 (2006.01); A61P 31/20 (2006.01); A61P 31/14 (2006.01);
U.S. Cl.
CPC ...
A61K 39/235 (2013.01); A61P 31/14 (2018.01); A61P 31/20 (2018.01); A61P 37/04 (2018.01); A61K 2039/545 (2013.01); A61K 2039/70 (2013.01);
Abstract
Compositions and methods are described for generating an improved effective immune response against an immunogen in humans. The enhanced immune response, is obtained by using an MVA vector as a prime, an adenovirus vector as a first boost, and an adenovirus vector as a second boost. The compositions and methods can be used to provide a protective immunity against a disease, such as an infection of one or more subtypes of Ebola and Marburg filoviruses, in humans.