The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2021

Filed:

Feb. 10, 2020
Applicant:

Liplasome Pharma Aps, Vejle, DK;

Inventors:

Anders Falk Vikbjerg, Greve, DK;

Sune Allan Petersen, Greve, DK;

Fredrik Melander, Malmö, SE;

Jonas Rosager Henriksen, Allerød, DK;

Kent Jørgensen, Bagsværd, DK;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 33/243 (2019.01); A61K 31/555 (2006.01); A61K 31/192 (2006.01); A61K 31/203 (2006.01); A61K 31/337 (2006.01); A61K 31/19 (2006.01); A61K 38/14 (2006.01); A61K 31/475 (2006.01); A61K 31/704 (2006.01); A61K 31/519 (2006.01); A61K 31/513 (2006.01);
U.S. Cl.
CPC ...
A61K 33/243 (2019.01); A61K 9/1271 (2013.01); A61K 31/19 (2013.01); A61K 31/192 (2013.01); A61K 31/203 (2013.01); A61K 31/337 (2013.01); A61K 31/475 (2013.01); A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61K 31/555 (2013.01); A61K 31/704 (2013.01); A61K 38/14 (2013.01);
Abstract

The present invention provides liposomes that are useful for delivery of bioactive agents such as therapeutics. Among others, the liposomes of the invention are capable of delivering their payload at sites of increased secretory phospholipase A2 (sPLA2) activity, because phospholipase A2 (PLA2) will hydrolyse lipids of the liposome. Thus, the liposomes of the invention may e.g. be used in relation to cancer therapy. Another aspect of the invention is a liposomal formulation comprising the liposome of the invention. Still another aspect is a method of producing a liposomal formulation of the invention.


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