The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 16, 2021
Filed:
Aug. 12, 2020
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Adastra Pharmaceuticals, Inc., Princeton, NJ (US);
Sameer Agnihotri, Pittsburgh, PA (US);
Alberto Broniscer, Pittsburgh, PA (US);
Ian F. Pollack, Pittsburgh, PA (US);
Thomas M. Estok, Lakewood Ranch, FL (US);
UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, Pittsburgh, PA (US);
ADASTRA PHARMACEUTICALS, INC., Princeton, NJ (US);
Abstract
The present disclosure relates to uses of TG02, for treating a glioma in a pediatric human subject. In certain embodiments, the glioma can be a pediatric high-grade glioma (PHGG), e.g., a diffuse intrinsic pontine glioma (DIPG), and/or a H3.3-mutated glioma (e.g., a H3K27M-mutated glioma). The present disclosure further provides pharmaceutical compositions and kits that include an ERK5 inhibitor.