The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 16, 2021

Filed:

Mar. 01, 2013
Applicant:

Rhodes Pharmaeuticals L.p., Coventry, RI (US);

Inventors:

Akwete L. Adjei, East Greenwich, RI (US);

Sibao Chen, Warwick, RI (US);

Robert J. Kupper, Warwick, RI (US);

Vincent Mancinelli, Scituate, RI (US);

Assignee:

Rhodes Pharmaeuticals, L.P., Coventry, RI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); A61K 9/28 (2006.01); A61K 9/16 (2006.01); A61K 45/06 (2006.01); A61K 9/20 (2006.01); A61K 9/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/485 (2013.01); A61K 9/1635 (2013.01); A61K 9/1676 (2013.01); A61K 9/1682 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/2077 (2013.01); A61K 9/2081 (2013.01); A61K 9/2095 (2013.01); A61K 9/2846 (2013.01); A61K 9/2853 (2013.01); A61K 9/5078 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed in certain embodiments is an immediate release solid oral dosage form comprising a plurality of particles, each particle comprising: (i) a core comprising a first active agent; (ii) a coating comprising a second active agent layered over the core; and (iii) a material that is sensitive to acidic pH layered over the coated core; wherein the dosage form releases at least about 70% of the second active agent within 45 minutes as measured by in-vitro dissolution in a USP Apparatus 2 (paddle) at 50 rpm in 500 ml 0.1 N HCl at 37° C.


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