IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11173145 B1

PDFFull Text
Date of Patent:
Nov. 16, 2021

Filed:

Jan. 16, 2018

Compounds useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase

Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Richard T. Lewis, Missouri City, TX (US);

Matthew Hamilton, Missouri City, TX (US);

Philip Jones, Houston, TX (US);

Alessia Petrocchi, Houston, TX (US);

Naphtali Reyna, Arlington, TX (US);

Jason Cross, Pearland, TX (US);

Michelle Han, Houston, TX (US);

Michael Soth, Sugar Land, TX (US);

Timothy McAfoos, Pearland, TX (US);

Martin Tremblay, Waltham, MA (US);

Assignee:

Board of Regents, The University of Texas System, Austin, TX (US);

Attorneys:

Dennis A. Bennett

Lauren L. Stevens

Cynthia Hathaway

Primary Examiner:

Paul V Ward

Int. Cl.
CPC ...
C07D 231/14 (2006.01); A61K 31/4192 (2006.01); A61P 35/00 (2006.01); A61K 31/166 (2006.01); A61K 31/18 (2006.01); A61K 31/351 (2006.01); A61K 31/4015 (2006.01); A61K 31/4184 (2006.01); A61K 31/4196 (2006.01); A61K 31/421 (2006.01); A61K 31/4245 (2006.01); A61K 31/437 (2006.01); A61K 31/4402 (2006.01); A61K 31/47 (2006.01); A61K 31/4706 (2006.01); A61K 31/4965 (2006.01); A61K 31/50 (2006.01); A61K 31/502 (2006.01); A61K 31/517 (2006.01); A61K 31/5375 (2006.01); C07C 231/14 (2006.01); C07C 307/02 (2006.01); C07D 209/38 (2006.01); C07D 215/42 (2006.01); C07D 235/08 (2006.01); C07D 237/24 (2006.01); C07D 237/28 (2006.01); C07D 239/88 (2006.01); C07D 241/24 (2006.01); C07D 249/04 (2006.01); C07D 249/08 (2006.01); C07D 263/22 (2006.01); C07D 295/195 (2006.01); C07D 309/12 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 413/12 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4192 (2013.01); A61K 31/166 (2013.01); A61K 31/18 (2013.01); A61K 31/351 (2013.01); A61K 31/4015 (2013.01); A61K 31/4184 (2013.01); A61K 31/4196 (2013.01); A61K 31/421 (2013.01); A61K 31/4245 (2013.01); A61K 31/437 (2013.01); A61K 31/4402 (2013.01); A61K 31/47 (2013.01); A61K 31/4706 (2013.01); A61K 31/4965 (2013.01); A61K 31/50 (2013.01); A61K 31/502 (2013.01); A61K 31/517 (2013.01); A61K 31/5375 (2013.01); A61P 35/00 (2018.01); C07C 231/14 (2013.01); C07C 307/02 (2013.01); C07D 209/38 (2013.01); C07D 215/42 (2013.01); C07D 235/08 (2013.01); C07D 237/24 (2013.01); C07D 237/28 (2013.01); C07D 239/88 (2013.01); C07D 241/24 (2013.01); C07D 249/04 (2013.01); C07D 249/08 (2013.01); C07D 263/22 (2013.01); C07D 295/195 (2013.01); C07D 309/12 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 413/12 (2013.01); C07D 471/04 (2013.01);
Abstract

Compounds of formula (VII), which are useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase, are provided. Also provided are pharmaceutical compositions, kits comprising said compounds, and methods and uses pertaining to said compounds.

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