The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2021
Filed:
May. 23, 2015
Grifols Diagnostic Solutions Inc., Emeryville, CA (US);
Peter Schwind, Fribourg, CH;
Ariane Caesar, Wuennewil, CH;
GRIFOLS DIAGNOSTIC SOLUTIONS INC., Emeryville, CA (US);
Abstract
The invention relates to a device for determining a cellular-bound analyte in a liquid sample, comprising a separation matrix with at least one indicator zone. The invention is characterized in that the indicator zone comprises a first antibody directed against the cellular-bound analyte or a fragment thereof and a binding element directed against the first antibody, the first antibody being an incomplete antibody. The separation matrix is preferably designed in the form of the membrane of a lateral flow assay device or as a gel matrix. In a particularly preferable manner, the device comprises a membrane () with a charging zone () for applying the liquid sample, at least one indicator zone which can interact with the cellular-bound analyte, and at least one absorption region () which absorbs the liquid after passing the indicator zone. The indicator zone lies between the charging zone () and the absorption region (). The invention is characterized in that the indicator zone comprises an antibody directed against the cellular-bound analyte or a fragment thereof and a binding element directed against the first antibody, the first antibody being an incomplete antibody.