The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2021
Filed:
Jan. 26, 2015
Applicant:
Synaffix B.v., Oss, NL;
Inventors:
Floris Louis Van Delft, Nijmegen, NL;
Frederik Jan Dommerholt, Beuningen, NL;
Assignee:
SYNAFFIX B.V., Oss, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07H 19/10 (2006.01); C07D 225/08 (2006.01); C07D 225/02 (2006.01); C07D 231/54 (2006.01); C07D 261/20 (2006.01); C07D 249/16 (2006.01); A61K 47/68 (2017.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); C07C 269/06 (2006.01); C07C 271/18 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 47/545 (2017.08); A61K 47/60 (2017.08); A61K 47/6855 (2017.08); C07C 269/06 (2013.01); C07C 271/18 (2013.01); C07D 225/02 (2013.01); C07D 225/08 (2013.01); C07D 231/54 (2013.01); C07D 249/16 (2013.01); C07D 261/20 (2013.01); C07H 19/10 (2013.01); C07K 14/473 (2013.01); C07C 2602/22 (2017.05); C07C 2603/50 (2017.05);
Abstract
A process is provided, comprising reacting a (hetero)aryl 1,3-dipole compound with a (hetero)cycloalkyne, wherein the (hetero)aryl 1,3-dipole compound comprises a 1,3-dipole functional group bonded to a (hetero)aryl group, and wherein the (hetero)aryl 1,3-dipole compound is a (hetero)aryl azide or a (hetero)aryl diazo compound; wherein: