The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2021
Filed:
Nov. 17, 2017
Applicant:
Eli Lilly and Company, Indianapolis, IN (US);
Inventors:
Yiqing Feng, Carmel, IN (US);
Philip Arthur Hipskind, New Palestine, IN (US);
Renhua Li, Fishers, IN (US);
Ling Liu, Carmel, IN (US);
Takako Wilson, Indianapolis, IN (US);
Aaron David Wrobleski, Indianapolis, IN (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6851 (2017.08); A61K 47/6871 (2017.08); A61P 35/00 (2018.01);
Abstract
Provided are antibody-drug conjugates (ADCs) that bind to, and kill MET expressing tumor cells, and that are effective in treating MET expressing cancers. Also provided are novel compounds and methods of conjugating MET antibodies to generate such ADCs.