The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 09, 2021

Filed:

Jun. 21, 2017
Applicant:

Seoul National University R&db Foundation, Seoul, KR;

Inventors:

Junho Chung, Gyeonggi-Do, KR;

Junyeong Jin, Gyeonggi-do, KR;

Hyori Kim, Seoul, KR;

Gunwoo Park, Gyeonggi-do, KR;

Soohyun Kim, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 47/65 (2017.01); A61P 35/00 (2006.01); A61K 31/407 (2006.01); A61K 31/4188 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); A61K 31/407 (2013.01); A61K 31/4188 (2013.01); A61K 47/65 (2017.08); A61K 47/6849 (2017.08); A61K 47/6879 (2017.08); A61P 35/00 (2018.01); C07K 16/2863 (2013.01); C07K 16/468 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/526 (2013.01); C07K 2317/56 (2013.01); C07K 2317/94 (2013.01);
Abstract

The present invention relates to an antibody drug conjugate using a bispecific antibody and its use. The antibody drug conjugate of the present invention can easily form a conjugate of an antibody and a drug without a multistep synthetic process though binding of a conjugate of a bivalent cotinine-peptide and a drug, and an anti-cotinine single chain variable fragment. In addition, the antibody drug conjugate can effectively deliver a drug to a target to which the antibody binds specifically, and can enhance a half-life of a drug in the body, thereby improving a therapeutic effect.


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