The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2021
Filed:
Oct. 16, 2019
Applicant:
Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;
Inventors:
Riccardo Giovannini, Biberach an der Riss, DE;
Angelo Ceci, Mittelbiberach, DE;
Cornelia Dorner-Ciossek, Warthausen, DE;
Roland Pfau, Biberach an der Riss, DE;
Dieter Wiedenmayer, Biberach an der Riss, DE;
Assignee:
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/06 (2006.01); A61P 25/24 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); C07D 413/06 (2013.01); A61K 45/06 (2013.01);
Abstract
Disclosed are 4-pyrazin-2-ylmethyl-morpholines of formula A and pharmaceutically acceptable salts thereof, wherein Rand Rare defined herein. Also disclosed are processes for their preparation, pharmaceutical compositions containing the compounds, and their use in therapy, particularly in the treatment or prevention of conditions having an association with NR2B negative allosteric modulating properties.