The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 09, 2021

Filed:

Jan. 09, 2017
Applicants:

Nexgen Biotechnologies, Inc., Seoul, KR;

Sun Kyo Lee, Gyeonggi-do, KR;

Inventors:

Sun Kyo Lee, Gyeonggi-do, KR;

Seong Ran Lee, Gyeonggi-do, KR;

Han Bong Ryu, Seoul, KR;

Tae Won Choi, Seoul, KR;

Tae Hyun Kim, Gyeonggi-do, KR;

Assignees:

Other;

NEXGEN BIOTECHNOLOGIES, INC., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/64 (2006.01); A61Q 19/08 (2006.01); A61Q 19/10 (2006.01); C07K 14/61 (2006.01); A61K 8/02 (2006.01); A61Q 19/00 (2006.01);
U.S. Cl.
CPC ...
A61K 8/64 (2013.01); A61K 8/0212 (2013.01); A61Q 19/007 (2013.01); A61Q 19/08 (2013.01); A61Q 19/10 (2013.01); C07K 14/61 (2013.01);
Abstract

A human growth hormone fusion protein has enhanced thermal stability. The human growth hormone fusion protein has the amino acid sequence SEQ ID NO: 3 or SEQ ID NO: 4. A gene encoding the human growth hormone fusion protein hascodon-optimized nucleotide sequence of SEQ ID NO: 5 or SEQ ID NO: 6. A recombinant vector includes the aforementioned gene. A host cell is transformed with the aforementioned recombinant vector. A method for producing in a host cell a human growth hormone fusion protein includes transforming a host cell with the aforementioned recombinant vector. The human growth hormone fusion protein may improve skin wrinkle and maintain skin elasticity. As the human growth hormone fusion protein has thermal stability and also has an effect of improving skin wrinkle and increasing the effect of maintaining skin elasticity, it can be advantageously used as a raw material of cosmetics.


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