The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
Nov. 30, 2017
International Business Machines Corporation, Armonk, NY (US);
Meenakshi Nagarajan, San Jose, CA (US);
Alix Lacoste, Brooklyn, NY (US);
International Business Machines Corporation, Armonk, NY (US);
Abstract
Utilizing a computing device to assist in repurposing of a pharmaceutical. An identification of a pharmaceutical for repurposing study is received by a computing device. A pharmaceutical expression signature is retrieved based upon the identification of the pharmaceutical, the pharmaceutical expression signature indicating differential expressions of a plurality of biomolecules regulated by the pharmaceutical. A plurality of disease expression signatures are retrieved from a disease omics database, each disease expression signature indicating differential expressions of a plurality of biomolecules affected by a disease. A pharmaceutical vector is generated based upon the pharmaceutical expression signature for the pharmaceutical. A plurality of disease vectors are generated based upon the plurality of disease expression signatures for each disease. N hypotheses correlating the pharmaceutical vector and one or more of the plurality of disease vectors are generated, each hypothesis indicating a potential repurposing for the pharmaceutical to treat the disease.