The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2021

Filed:

Dec. 10, 2018
Applicant:

International Business Machines Corporation, Armonk, NY (US);

Inventors:

Yann Astier, Irvington, NY (US);

Stacey M. Gifford, Ridgefield, CT (US);

Benjamin H. Wunsch, Mt. Kisco, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56983 (2013.01); B01L 3/502753 (2013.01); B01L 3/502761 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/0652 (2013.01); G01N 2469/10 (2013.01);
Abstract

Techniques for detection of virus-antibody nanocomplexes using a chip-based pillar array are provided. In one aspect, a method for virus detection is provided. The method includes the steps of: collecting a fluid sample from a virus-bearing source; contacting the fluid sample with an antibody that binds to viruses to form a sample-antibody mixture, wherein the antibody is labeled with a fluorescent tag; separating particles including any antibody-virus complexes, if present, from the sample-antibody mixture using an assay nanopillar array; and detecting the antibody-virus complexes, if present, in the particles from the separating step using fluorescence. A virus detection chip device and a chip-based immunoassay method are also provided.


Find Patent Forward Citations

Loading…