The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
May. 08, 2020
Applicant:
Gen-probe Incorporated, San Diego, CA (US);
Inventors:
Jijumon Chelliserry, San Diego, CA (US);
Kui Gao, San Diego, CA (US);
Jeffrey M. Linnen, Poway, CA (US);
Assignee:
GEN-PROBE INCORPORATED, San Diego, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6893 (2018.01); C12N 1/06 (2006.01); G01N 33/48 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6893 (2013.01); C12N 1/06 (2013.01); C12Q 1/6806 (2013.01); G01N 33/48 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The invention provides a lysis reagent for lysing red blood cells, thereby releasing a target, such as RNA from a parasitic organism, in a form suitable for analysis. The reagent includes at least ammonium chloride and an anionic detergent, and may include an anti-coagulant. The reagent serves to lyse red blood cells, protect the released target from degradation in the lysate, and is compatible with subsequent steps for analysis of the target such as target capture, amplification, detection, or sequencing.