The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
Jan. 23, 2018
Applicant:
Olipass Corporation, Yongin-si, KR;
Inventors:
Shin Chung, Yongin-si, KR;
Daram Jung, Hwaseong-Si, KR;
Bongjun Cho, Yongin-Si, KR;
Kangwon Jang, Yongin-Si, KR;
Hyun Ju Jeon, Yongin-Si, KR;
Jinyoung Bae, Yongin-Si, KR;
Taeyeon Bae, Yongin-Si, KR;
Yeasel Jeon, Yongin-Si, KR;
Jun Yeon Lee, Yongin-Si, KR;
Sun Hwa Park, Siheung-Si, KR;
Dan Bi An, Yongin-Si, KR;
Assignee:
OliPass Corporation, Yongin-si, KR;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); C07K 14/003 (2013.01); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/3181 (2013.01); C12N 2310/333 (2013.01); C12N 2310/334 (2013.01); C12N 2310/335 (2013.01); C12N 2310/336 (2013.01); C12N 2320/33 (2013.01);
Abstract
The current invention provides peptide nucleic acid derivatives targeting the 3' splice site of exon 4 in the human SCN9A pre-mRNA. The peptide nucleic acid derivatives potently induce SCN9A mRNA splice variant(s) lacking the SCN9A exon 4 in cells, and are useful to safely treat pains or conditions involving Na1.7 activity.