The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
Jan. 06, 2020
Institut Gustave-roussy, Villejuif, FR;
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Assistance Publique—hopitaux DE Paris, Paris, FR;
Universite DE Versailles—st Quentin En Yvelines, Versailles, FR;
Universite Paris—sud, Orsay, FR;
William Vainchenker, Paris, FR;
Valerie Ugo, Brest, FR;
Chloe James, Creon, FR;
Jean-Pierre Le Couedic, Champs sur Marne, FR;
Nicole Casadevall, Paris, FR;
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS, Paris, FR;
INSTITUT NATIONAL DE LA SANTE DE LA RECHERCHE MEDICALE (INSERM), Paris, FR;
INSTITUT GUSTAVE-ROUSSY, Villejuif, FR;
UNIVERSITE DE VERSAILLES-ST QUENTIN EN YVELINES, Versailles, FR;
UNIVERSITE PARIS-SUD, Orsay, FR;
Abstract
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative disorders, or to the detection of the JAK2 V617F variant in myeloproliferative disorders allowing their reclassification in a new nosological group.