The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 2021
Filed:
Jan. 22, 2018
Jilin Asymchem Laboratories Co., Ltd., Jilin, CN;
Hao Hong, Morrisville, NC (US);
Gage James, Morrisville, NC (US);
Jiangping Lu, Tianjin, CN;
Xingfu Xu, Tianjin, CN;
Wenyan Yu, Tianjin, CN;
Na Zhang, Tianjin, CN;
Yulei Ma, Tianjin, CN;
Yibing Cheng, Tianjin, CN;
Huiyan Mu, Tianjin, CN;
JILIN ASYMCHEM LABORATORIES CO., LTD., Jilin, CN;
Abstract
A ketoreductase mutant and use thereof are provided. The amino acid sequence of the ketoreductase mutant is an amino acid sequence obtained by mutation of the amino acid sequence shown in SEQ ID NO: 1, wherein the mutation at least comprises one of the following mutation sites: position 6, position 94, position 96, position 117, position 144, position 156, position 193, position 205, position 224, position 176, position 85 and position 108; alternatively, the amino acid sequence of the ketoreductase mutant has a mutation site in a mutated amino acid sequence and an amino acid sequence having 80% or more homology with the mutated amino acid sequence.