The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 2021

Filed:

May. 09, 2016
Applicant:

Chonnam National University Hospital, Gwangju, KR;

Inventors:

Youngkeun Ahn, Gwangju, KR;

Yong Sook Kim, Gwangju, KR;

Dong Im Cho, Gwangju, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); A61K 35/34 (2015.01); A61K 31/454 (2006.01); A61K 35/28 (2015.01); A61K 31/395 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); A61K 31/395 (2013.01); A61K 31/454 (2013.01); A61K 35/28 (2013.01); A61K 35/34 (2013.01); C12N 5/0653 (2013.01); C12N 5/0654 (2013.01); A61K 9/0019 (2013.01); C12N 2501/065 (2013.01); C12N 2501/999 (2013.01); C12N 2506/1353 (2013.01);
Abstract

The present invention relates to an apicidin composition for inducing differentiation of mesenchymal stem cells into cardiac-committed cells, and a method for inducing differentiation into cardiac-committed cells using the same. The present invention allows mesenchymal stem cells to be specifically induced to differentiate into cardiac-committed cells even when an apicidin is treated for only a very short period of time of 24 hours, thereby being capable of solving the extremely low cardiomyogenic differentiation efficiency of mesenchymal stem cells, high cost, and long-term problems in the conventional art, and thus the present invention can be usefully used for treating heart disease.


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